Coats disease is a form of retinal telangiectasia with lipid-rich subretinal exudates. Coats disease is a rare congenital nonhereditary eye disorder causing full or partial blindness characterized by abnormal development of blood vessels behind the retina.
Figure 1 From Coats Disease Of Adult Onset Semantic Scholar
Whereas simple Coats disease almost exclusively occurs unilaterally and in males both sexes and both eyes may have Coats retinal lesions in this syndrome.

Coats disease in adults. What causes Coats Disease. 1 The mainstay of management of Coats disease is photocoagulation to treat the nonperfused retina and to obliterate the aneurysms and leaking vessels. Coats disease is an eye disorder characterized by abnormal development of the blood vessels in the retina retinal telangiectasia.
When this entity appears in adults it usually exhibits a more benign clinical course. Coats disease lesions may also occur in Labrune syndrome 614561 and of course in isolation. It most often appears at 8-10 years of age affects males three times more often than females and usually affects only one eye.
The majority of Coats disease is diagnosed between ages 8 and 16. Coats disease can also fall under glaucoma. 8 This contrasted with the Shields series in childhood Coats where macroaneurysms with retinal hemorrhages were only present in 13 of cases.
Coats disease also known as exudative retinitis is an uncommon eye condition that affects the smaller blood vessels capillaries found in the retina. Coats disease is a rare condition in which abnormal blood vessels in the retina dilate and leak fluid resulting in damage to the retina and possibly vision loss. Early signs and symptoms vary but may include vision loss crossed eyes strabismus and a white mass in the pupil behind the lens of the eye leukocoria.
Four of our patients did develop exudative RDs but these detachments responded well to laser treatment and no patient developed neovascular glaucoma. Coats disease is an idiopathic condition characterized by retinal telangiectasia with intra- and subretinal exudation leading to exudative retinal detachment without any signs of vitreoretinal traction. It usually occurs in males between 4 and 10 years of age and is unilateral in 80 of cases.
In a series of adult-onset Coats disease 77 of cases demonstrated arterial macroaneurysms associated with intraretinal hemorrhages suggestive of prior rupture. Its more frequent in males at least 31 than females and in patients younger than 8 years old even though it has been observed in infants as well as older patients. 1 Alternative diagnoses should especially be considered in female adult-onset or bilateral cases.
It is a rare condition affecting 1 in 100000 people. It is mainly a disease of childhood and only on rare occasions has it been described in adults. Coats disease is a rare eye disorder involving abnormal development of blood vessels in the retina.
In adults it typically has a more insidious clinical course. Located in the back of the eye the retina sends light images to the brain and is essential to. 12 Anti-VEGF injections and periocular.
Most people begin showing symptoms in childhood. It can have a similar presentation to that of retinoblastoma. Coats disease can make these blood vessels weak and grow incorrectly causing them to leak fluid and blood under the retina.
The retina is the light-sensitive layer that lines the inside of your eye. Adult-onset Coats disease has less extensive involvement more benign natural course and a more favorable treatment outcome as against the childhood-onset disease. Coats disease is a retinal vascular abnormality characterized by idiopathic retinal vascular telangiectasia and microvascular aneurysmal changes that can cause exudation and exudative retinal detachment.
Coats disease is usually characterized by unilateral 95 progressive development of abnormal vessels in the retina of the affected individuals. The vast majority of Coats disease is diagnosed in the first decade of life although mild forms of the condition can present well into adulthood45 The disease occurs sporadically and no hereditary pattern has been identified despite reports that individual cases of Coats disease have occurred as a result of localized mutations in proteins governing angiogenesis6 More than 75 percent of. Diagnosis of this condition must be.
1 There are reports of cases presenting in adulthood but this is less common. Coats disease is much more common in males than females. It is most commonly discovered in children before the age of 10 years but can present in adulthood too.
Most cases of Coats disease are diagnosed in childhood. Coats disease in adults seems to advance at a slower rate than it does in children with the majority of patients reaching a stable final VA. 78 Greater than 75 percent of patients are male and 95 percent of cases are unilateral.
Coats disease diagnosed in adulthood is an idiopathic retinal exudative vascular disease without an inciting factor and has retinal features different from the childhood disease.
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