The exact mechanism leading to an increased alkaline phosphatase level in patients with liver congestion is unknown. Elevated alkaline phosphatase is associated with numerous signs and symptoms.

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In most cases higher levels of alkaline phosphates are closely associated with bone disorders liver damage liver disease or a blocked bile duct.

Alkaline phosphatase levels high. High alkaline phosphatase doesnt cause any symptoms directly. Increased serum intestinal ALP levels may occur with intestinal disease or as a familial benign entity. Also it usually occurs in other acute diseases.

Alkaline phosphatase is high if the blood levels surpass 130 UL. Elevated levels are also associated with diabetes hypertension and cardiovascular disease. Dicken Weatherby a naturopathic physician and author of the textbook Blood Chemistry and CBC Analysis alkaline phosphatase is a group of isoenzymes that originate in your bone liver intestines skin and placenta.

Normal levels of alkaline phosphatase Alkaline phosphatase can be found in higher normal concentrations in the following parts of the body. In most instances high ALP is a temporary and non-serious concern. Increased serum renal ALP levels may be encountered in renal diseases.

Alkaline Phosphatase ALP is an enzyme found in all body tissue but primarily in bones bile ducts and the liver. This is due to the inflammation of the organ and the overproduction of bilirubin. The symptoms will depend on your underlying health issuesuch as liver or bone disorders.

High levels Higher-than-normal levels of ALP in your blood may indicate a problem with your liver or gallbladder. Alkaline phosphatase ALP is an enzyme naturally found in your liver digestive system kidney and bones. A high level may indicate bone liver or bile duct disease.

ALP plays a role in numerous processes in the human body and any abnormalities in blood concentrationseither high or lowmay be indicative of diseases ranging from gallstones and thyroid disease to hepatitis and cancer. Elevated ALP can indicate the presence of a wide range of liver diseases. A high ALP may indicate health conditions including liver damage liver disease bone disease or a blocked bile duct.

It was found that elevated levels are associated with elevated serum C-reactive protein CRP which could reflect an inflammatory and atherogenic milieu possibly an alternative cause for elevated serum alkaline phosphatase. If you show signs of liver disease or a bone disorder your doctor may order an alkaline phosphatase ALP test to measure the amount of the enzyme in your blood and help in diagnosing the problem. Alkaline phosphatase levels can change and increase as a consequence of different liver diseases.

These include fatty liver cirrhosis of the liver hepatitis liver cancer cholestasis and others. When present the elevation is mild usually not exceeding twice the upper limit of normal unless the liver disease and heart failure have a common cause. The increased levels of this enzyme can be lowered by an appropriate treatment of the underlying disorder along with certain dietary changes and lifestyle modifications.

As ALP is most abundant in the bones and liver elevated ALP levels are generally a sign of a liver or bone condition. Some drugs may also cause increased levels. Because an elevated alkaline phosphatase or ALP level can be associated with different medical conditions like rickets cirrhosis hepatitis bone cancer Pagets disease hyperparathyroidism and a deficiency in vitamin D symptoms and treatment options are different and dependent on the specific cause as noted by WebMD.

Elevated alkaline phosphatase levels are uncommon in heart failure. Liver damage creates a different type of ALP than bone disorders do. Consider growth spurts in adolescents pregnancy in women drugs and age related increases.

Abnormal ALP levels indicate that a person may have gallstones. If alkaline phosphatase is raised in an asymptomatic patient and serum bilirubin liver transaminases creatinine adjusted calcium thyroid function and blood count are normal 2. High alkaline phosphatase symptoms include fatigue and weakness nausea and vomiting weight loss fever itching yellow skin dark urine abdominal pain and many more.

High alkaline phosphatase levels may mean there is damage to your liver or that you have a type of bone disorder. Not only do the transaminases increased but also this enzyme. Outside pregnancy increased levels of serum placental ALP may be due to tumour secretion but rarely increases the total serum level.

Alkaline phosphatase ALP is an enzyme found in the blood that helps break down proteins. Elevated alkaline phosphatase levels may be the result of liver diseases poor bone health or deficiency of vitamin D. Liver bile duct kidney bone intestinal mucosa and placenta.

Causes Of Elevated Alkaline Phosphatase Liver Conditions ALP can be elevated due to damage to liver cells. This is the case for example for viral hepatitis. This could include hepatitis cirrhosis liver cancer gallstones or a blockage.

If the test results show high alkaline phosphatase levels your health care provider may order additional tests to find out where the extra ALP is coming from. In healthy adults the normal levels of alkaline phosphatase vary between 20 and 140 IUL.